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- Keywords DNA methylation;anti-BPDE;nickel sulfide;genome; DNA甲基化;反式二氢二醇环氧苯并芘;硫化镍;基因组;
- Keywords DNA methylation;melting curve analysis;bisulfite;androgen receptor; DNA甲基化;链融解曲线法;亚硫酸氢盐;雄激素受体;
- Keywords DNA methylation;DNA methyltransferases;transcriptional silencing; DNA甲基化;DNA甲基转移酶;转录抑制;
- Keywords DNA methylation;epigenetics;forensic medicine;genetic marker; DNA甲基化;表遗传学;法医学;遗传标记;
- Keywords DNA methylation;hypermethylation;hypomethylation;gene stability;tumorigenesis; DNA的甲基化;高甲基化;低甲基化;基因稳定性;肿瘤发生;
- Keywords DNA methyltransferase;DNA methylation;G/T mismatch repair;thymine DNA glycosylase; DNA甲基转移酶;DNA甲基化;G/T错配修复;DNA胸腺嘧啶糖基化酶;
- Keywords DNA methylferase 3b;gene;antisense technology;expression vector;gene cloning;DNA methylation; 反义技术;表达载体;基因克隆;DNA甲基化;
- Keywords DNA methylation;microarray;immunoprecipitation;restriction enzyme;carcinoma; DNA甲基化;芯片;免疫沉淀;限制性内切酶;癌症;
- Keywords DNA methylation;epigenetics;adenomatous polyposis coli (APC);lung cancer;methylation specific PCR (MSP);quality control; 关键词DNA甲基化;表观遗传;APC基因;肺癌;甲基化特异性PCR;质量控制;
- Focus on the bioinformatics analysis of DNA methylation. 甲基化的生物信息学分析。
- DNA methylation is a frequent change in epigenetics of leukemia. 摘要DNA甲基化是白血病表观遗传学改变中较常见的改变。
- DNA methylation plays a key role in transgene silencing. DNA甲基化是引起外源基因沉默的主要原因。
- DNA methylation and its aberrance play an important role in the human development and tumorigenesis. DNA的甲基化及甲基化异常在人体发育和肿瘤的发生中起着至关重要的作用。
- DNA methylation patterns in the CpG island of RASGRF2, RASGRF2 and FBN2 were determined by the method of MSP. 采用 MSP分析 RASSF1A、 RASGRF2 和 FBN2 是否存在启动子异常甲基化。
- Alterations in DNA methylation, an important regulator of gene transcription, lead to cancer. 对调节基因转录起重要作用的DNA甲基化的异常将导致癌症的发生。
- Recent studies on DNA methylation and its regulatory enzymes,seem hot to researches of epigenetics. DNA甲基化及其调节酶是近年来表观遗传学研究的热点。
- The abnormality of DNA methylation includes global hypomethylation and region-specific hypermethylation. DNA甲基化异常包括全基因组的低甲基化和局部基因的高甲基化。
- The advent of microarray technology has provided new opportunities for high-throughput study on DNA methylation. 芯片技术的发展为高通量研究DNA甲基化提供了新的方法。
- DNA methylation is a kind of normal endogenous modified mode,which is fulfilled by DNA methylation transferase. DNA甲基化是真核生物DNA的正常内源性修饰方式,它由DNA甲基化转移酶催化发生。
- In recent years, a variety of methods have been developed to study DNA methylation and other epigenetic modification. 随着研究的不断深入,各种研究方法被开发出来以满足不同类型研究的需要。